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April 1980

Immunofluorescent Studies of the Eye in Waldenström's Macroglobulinemia

Author Affiliations

From the Departments of Ophthalmology (Drs Friedman and Odel) and Pathology (Drs Marchevsky, Gerber, and Thung), The Mount Sinai School of Medicine of the City University of New York.

Arch Ophthalmol. 1980;98(4):743-746. doi:10.1001/archopht.1980.01020030737020

• The eyes of a 53-year-old woman with K light chain macroglobulinemia were studied histopathologically. Retinal hemorrhages were observed on gross examination. Microscopic examination disclosed eosinophilic, PAS-positive deposits in cystoid spaces within the outer plexiform layer, in the inner retina, and about photoreceptors. Immunofluorescent studies showed that the deposits contained IgM. Aneurysmal dilations of small retinal vessels were demonstrated as well.

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