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June 1980

Possible Mechanism for Corneal Complication Caused by an Intraocular Lens

Arch Ophthalmol. 1980;98(6):1134. doi:10.1001/archopht.1980.01020031124028

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To the Editor.  —I have read with interest the article entitled "Methylmethacrylate Monomer in Intraocular Lenses of Polymethylmethacrylate: Cellular Toxicity" by Turkish and Galin (Archives 98:120-121, 1980).This article and previous publications by Turkish and Galin and their associates seem to absolve the residual monomer as the cause of some of the difficult-to-explain corneal complications after intraocular lens (IOL) implantation, that is, those corneal complications that reverse themselves after IOL removal. The manufacture, the method of sterilization of the IOL, the surgical procedure, and the surgeons themselves provide multiple variables that are difficult to identify when attempting to find the cause of some of these complications. In such cases, it is usually assumed that the lens is leaching some kind of toxic substance that affects the corneal endothelium. I have encountered similar situations when some clinicians were trying to explain some conjunctival complications caused by contact lenses.In either case,

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