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To the Editor.
—I enjoyed reading the letter of Sohan Singh Hayreh, MD, entitled "Ocular Neovascularization" in the March Archives (98:574,1980). I think Dr Hayreh makes some interesting points and observations in his letter. In his last paragraph, he notes that we should stop blaming the retinal capillary obliteration and hypoxic retinal tissue for neovascularization and start blaming chronic leaking retinal capillaries. I pointed out in the Krill Lecture, which appeared in the American Journal of Ophthalmology (85:287, 1978), that for retinal neovascularization to develop, one needed both a stimulus and a diseased retinal vascular bed. I think that this concept is tenable and compatible with Dr Hayreh's hypothesis. He states that his hypothesis is presented to be provocative and to redirect our line of thinking from well-worn tracks. Had Dr Hayreh broadened his list of references, he might have found that the tracks were perhaps a little less well
Henkind P. Ocular Neovascularization. Arch Ophthalmol. 1980;98(8):1488. doi:10.1001/archopht.1980.01020040340028
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