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September 1980

Comparative Ocular Pressure Elevation by Medrysone, Fluorometholone, and Dexamethasone Phosphate

Author Affiliations

From the Ophthalmology Section (Dr Mindel and Ms Walker) and Psychiatry Department (Dr Tavitian) Bronx Veterans Hospital; and Departments of Ophthalmology, Pharmacology (Dr Mindel), and Biostatistics (Dr Smith), The Mount Sinai School of Medicine, New York.

Arch Ophthalmol. 1980;98(9):1577-1578. doi:10.1001/archopht.1980.01020040429006

• In age-, race-, and sex-matched groups, the relative abilities of medrysone, fluorometholone, and dexamethasone phosphate to elevate intraocular pressure were compared in a masked manner. Compliance was controlled by drops being given by nursing personnel. The 18 male hospitalized volunteers received commercial preparations of one of the corticosteroids to each eye four times a day for six weeks. The relative ability of medrysone, fluorometholone, and dexamethasone phosphate to raise IOP was 1, 4, and 7.6, respectively.

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