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January 1981

Prevalence of Chorioretinal Scars Associated With Coccidioidomycosis

Author Affiliations

From the Section of Ophthalmology, Department of Surgery (Drs Rodenbiker and Ganley), and the Section of Infectious Diseases, Department of Internal Medicine (Drs Galgiani and Axline), Veterans Administration Medical Center; and the University of Arizona Health Sciences Center, Tucson. Dr Ganley is now with the Louisiana State University Medical Center, Shreveport.

Arch Ophthalmol. 1981;99(1):71-75. doi:10.1001/archopht.1981.03930010073005

• A retrospective study was conducted to determine the prevalence and spectrum of chorioretinal involvement among individuals with previously documented systemic coccidioidomycosis. Fifty-four subjects were given a modified ocular examination, and their medical records were abstracted for clinical classification of the disease and its correlation with ocular findings. Five of 54 subjects with documented past infection with Coccidioides immitis had characteristic inactive peripheral chorioretinal scars. No relationship between the presence of scars and the extent of disease was evident; typical scars were found in patients who had experienced mild respiratory tract infection as well as in more extensively disseminated disease. We conclude that dissemination of C immitis to the eye can occur during benign pulmonary coccidioidomycosis as well as with more severe systemic disease, and the prevalence of chorioretinal lesions is more common than isolated case reports would indicate.