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April 1981

Prostaglandins and Related Lipids: Prostaglandin Synthetase Inhibitors-New Clinical Applications

Arch Ophthalmol. 1981;99(4):706. doi:10.1001/archopht.1981.03930010706041

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This book presents the proceedings of a symposium on prostaglandins and human medicine that was held in Paris, Sept 27-28, 1979.

One of the articles is by Bechetoille and Baikoff. They discuss the role of prostaglandins as mediators of the ocular response to trauma (including surgical trauma). They used, in a controlled study, indomethacin after cataract extractions and evaluated the postoperative inflammatory response by fluorography of the anterior segment. α-Chymotrypsin was used for the cataract extraction, and the treated patients showed less of an increase in their intraocular pressure and less of a breakdown in their blood ocular barriers.

Another article of ophthalmic interest proved that indomethacin has no influence on thyroid function in Graves' disease.

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