• Reticulum cell sarcoma involving the vitreous and the brainstem occurred in a 45-year-old man. He initially was seen with diplopia from a partial left-sided third cranial nerve palsy, which is rare. Later, a typical uveitis developed in the right eye. An initial diagnosis of brainstem glioma, based primarily on the computed tomographic scan findings and clinical history, was ultimately proved erroneous when the correct diagnosis was shown by the results of a cytologic examination of a vitreous aspirate. Excellent visual response to a moderately high oral dose of steroids occurred, which has not been usual in other reported cases. Definitive cobalt (gamma) radiation therapy (6,000 rad to the brainstem and 4,000 rad to the vitreous) has produced a one-year remission at this time.
Sloas HA, Starling J, Harper DG, Cupples HP. Update of Ocular Reticulum Cell Sarcoma. Arch Ophthalmol. 1981;99(6):1048–1052. doi:10.1001/archopht.1981.03930011048013
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.