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August 1981

Unilateral Proliferative Diabetic Retinopathy: I. Initial Findings

Author Affiliations

From the Department of Retina Research, Eye Research Institute of Retina Foundation (Drs McMeel, Valone, and Franks); Retina Associates (Dr McMeel); Massachusetts Eye and Ear Infirmary (Drs McMeel and Valone); and the Department of Ophthalmology, Harvard University Medical School (Drs McMeel and Valone), Boston. Dr Valone is now with the Eastern Virginia Medical School, Norfolk.

Arch Ophthalmol. 1981;99(8):1357-1361. doi:10.1001/archopht.1981.03930020231002

• The combination of unilateral proliferative diabetic retinopathy (PDR) in one eye and nonproliferative diabetic retinopathy (NPDR) in the fellow eye was observed in 10.1% of patients with PDR. Most patients were between the ages of 50 and 70 years; the majority had adultonset diabetes mellitus. Unilateral aphakia and anisometropia of greater than 1 diopter were both infrequently seen. The incidence of glaucoma was unremarkable. Unilateral elevated—but not necessarily abnormal—intraocular pressure was found in a significantly larger proportion of eyes with NPDR (20%) than with PDR (12%). Most patients had moderate to severe angiopathy or exudation in the eye with NPDR and modest PDR in the fellow eye; however, one third had moderate to severe PDR. In only 2% of the patients was visual acuity less than 20/200 on initial examination.