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August 1981

Cornea Pseudoguttata: A Clinical and Histopathologic Description of Endothelial Cell Edema

Author Affiliations

From the Iowa Lions Cornea Center, Department of Ophthalmology, University of Iowa Hospitals, Iowa City.

Arch Ophthalmol. 1981;99(8):1377-1381. doi:10.1001/archopht.1981.03930020251007

•ea guttata is a well-well-recognized corneal condition that is characterized by localized thickenings of Descemet's membrane. When these lesions disrupt, the regular endothelial mosaic, dark spots are seen in specular reflection. This same clinical appearance can be present during shortshort-termitis and corneal inflammation. Since it disappears with resolution of the inflammation, true corneattata (thickening of Descemet's membrane) obviously does not occur. Three cases of this transient clinical entity occurred. Production of iritis and corneal inflammation in rabbits with the use of bovine serum albumin and cautery resultede same transient appearance of dark spots, which interrupted the normal endothelial mosaic seen in specularflection. Scanning and transmission electron microscopy of the cornea "pseudoguttata" transient endotheliall edema.

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