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March 1982

T and B Lymphocytes in the Aqueous Humor of Patients With Uveitis

Author Affiliations

From the Departments of Ophthalmology (Dr Belfort) and Immunology (Drs Moura and Mendes), Escola Paulista de Medicina, São Paulo, Brazil.

Arch Ophthalmol. 1982;100(3):465-467. doi:10.1001/archopht.1982.01030030467019

• Sixteen patients with different types of uveitis (ocular toxoplasmosis, chronic cyclitis, Vogt-Koyanagi-Harada syndrome, Behçet's syndrome, ocular herpes, and a probable nematode) had the aqueous humor withdrawn and had the number of T, B, and null lymphocytes assessed. T and B lymphocytes were identified by rosette formation with sheep erythrocytes and with human erythrocytes sensitized with IgM antibody and complement or zymosan-C3 complexes, respectively. A much higher number of T lymphocytes than B lymphocytes was observed in all cases. The results were not influenced by treatment with steroids or immunosuppressive drugs for local, periocular, or systemic effects.

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