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April 1982

Keratoplasty Procedures

Author Affiliations

Gainesville, Fla

Arch Ophthalmol. 1982;100(4):665. doi:10.1001/archopht.1982.01030030667031

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To the Editor.  —In the December issue of the Archives (1978;96:2231-2233), Zimmerman and co-workers reported a prospective randomized study of 92 consecutive penetrating keratoplasty procedures done from May 10,1977, to Aug 25, 1977.This study compared postoperative intraocular pressures after the transplantation of donor buttons 0.5 mm in diameter larger than the recipient bed.

Method.  —One patient who underwent a penetrating keratoplasty on Aug 16, 1977, by Drs Olson and Kaufman and who must have been included in the transplant size study data pool was simultaneously enrolled by the surgeons in a double-blind study comparing the effect of timolol maleate and dichlorphenamide on postoperative IOP after penetrating keratoplasty. This patient, and all other patients in the study using timolol and dichlorphenamide, was randomly assigned and received one of four possible combinations after surgery: a vehicle plus a plain tablet, timolol plus a plain tablet, a vehicle plus dichlorphenamide, or timolol

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