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May 1982

Combined Use of Neostigmine and Ocular Motility Measurements in the Diagnosis of Myasthenia Gravis

Author Affiliations

From the Neuro-ophthalmology Unit, the Wilmer Ophthalmological Institute, The Johns Hopkins Hospital, Baltimore.

Arch Ophthalmol. 1982;100(5):761-763. doi:10.1001/archopht.1982.01030030765008

• Forty-four patients with diplopia caused by myasthenia gravis, ocular myopathies, and ocular motor nerve palsies underwent complete orthoptic evaluations before and after intramuscular injection of neostigmine (Prostigmin) methylsulfate. A test score combining the results of binocular and uniocular measurements was developed that allowed correct classification of 70% (31) of patients studied.

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