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June 1982

Clinicohistopathologic Correlations in Xerophthalmic Ulceration and Necrosis

Author Affiliations

From the International Center for Epidemiologic and Preventive Ophthalmology (ICEPO), The Johns Hopkins Medical Institutions, Baltimore, the Nutritional Blindness Prevention Project, Bandung, Indonesia, and Helen Keller International, New York (Dr Sommer); the Eye Pathology Laboratory, Wilmer Institute, The Johns Hopkins Hospital, Baltimore (Dr Green);; and the Department of Ophthalmology, Harvard Medical School, the Cornea Service, Massachusetts Eye and Ear Infirmary, and the Department of Cornea Research, Eye Research Institute of Retina Foundation, Boston (Dr Kenyon).

Arch Ophthalmol. 1982;100(6):953-963. doi:10.1001/archopht.1982.01030030961014

• Corneal tissue from five eyes of three children with active xerophthalmic keratopathy and stromal loss was studied histopathologically. Stromal dissolution was strikingly focal, sometimes occurring beneath an intact epithelium and often, though not always, accompanied by extensive inflammatory reaction and bacteria.

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