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November 1982

Longer Follow-up Periods for Treatment of Uveal Melanoma

Arch Ophthalmol. 1982;100(11):1855. doi:10.1001/archopht.1982.01030040835030

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To the Editor.  —I would like to comment on the article by Gragoudas et al entitled "Proton Beam Irradiation of Uveal Melanomas: Results of 5½-year Study," published in the June Archives (1982;100:928-934).The title suggests that the authors studied patients with uveal melanomas for 5½ years. However, the article describes only one patient studied for 5½ years and only 19 patients followed up for more than two years. Do the authors truly believe that the results of 19 patients treated for two years indicates the success of their modality?Those of us working with patients with melanoma are aware that even patients with proved metastatic disease frequently survive more than two years after the diagnosis of metastasis. My argument is this: a two-year follow-up for rhabdomyosarcoma is tantamount to a cure; a three-year follow-up for retinoblastoma is almost synonymous with a cure; and a two-year follow-up for melanoma is simply

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