• Comparisons were made between the ocular hypotensive effects and blood levels achieved with the single-dose administration of either generic acetazolamide or brand-name acetazolamide (Diamox). The relative cost of the two products was surveyed. The effect of food on the absorption of acetazolamide was also evaluated. The generic and brand-name acetazolamide were equivalent in their effects on intraocular pressure. Comparable blood levels of acetazolamide were obtained with the two products. The cost of generic acetazolamide was 37% less than brand-name acetazolamide, when available. Food intake did not appear to influence the absorption of acetazolamide.
Ellis PP, Price PK, Kelmenson R, Rendi MA. Effectiveness of Generic Acetazolamide. Arch Ophthalmol. 1982;100(12):1920–1922. doi:10.1001/archopht.1982.01030040900006
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