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December 1982

Effectiveness of Generic Acetazolamide

Author Affiliations

From the Department of Ophthalmology, University of Colorado Health Sciences Center, Denver.

Arch Ophthalmol. 1982;100(12):1920-1922. doi:10.1001/archopht.1982.01030040900006

• Comparisons were made between the ocular hypotensive effects and blood levels achieved with the single-dose administration of either generic acetazolamide or brand-name acetazolamide (Diamox). The relative cost of the two products was surveyed. The effect of food on the absorption of acetazolamide was also evaluated. The generic and brand-name acetazolamide were equivalent in their effects on intraocular pressure. Comparable blood levels of acetazolamide were obtained with the two products. The cost of generic acetazolamide was 37% less than brand-name acetazolamide, when available. Food intake did not appear to influence the absorption of acetazolamide.