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February 1983

Analysis of Characteristic Eye Movement Abnormalities in Internuclear Ophthalmoplegia

Author Affiliations

From the Department of Ophthalmology, Jules Stein Eye Institute (Drs Crane, Yee, and Hepler), and the Department of Neurology, Reed Neurological Research Center (Dr Baloh), UCLA Center for the Health Sciences.

Arch Ophthalmol. 1983;101(2):206-210. doi:10.1001/archopht.1983.01040010208004

• Quantitative electro-oculographic recording techniques were used to analyze four characteristic eye movement abnormalities in 21 patients with internuclear ophthalmoplegia (INO). The frequency of each of the abnormalities was determined to suggest a pattern that is the most sensitive in detecting the syndrome of INO. Slowing of the adducting saccade was the most frequently found abnormality, being present in all patients. The other characteristic eye movement disorders were found less frequently: dissociated nystagmus at 30° of eccentric gaze, dysmetria of the abducting eye, and limitation of adduction. The most sensitive pattern for detecting an INO seems to be slowing of the adducting saccade combined with either dissociated nystagmus or dysmetria of the abducting eye. Limitation of adduction was seen much less frequently.