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March 1983

Detection of Toxoplasmal Antigen and Antibody in Ocular Fluids in Experimental Ocular Toxoplasmosis

Author Affiliations

From the Francis I. Proctor Foundation for Research in Ophthalmology and the Department of Ophthalmology, University of California, San Francisco (Drs Rollins, Tabbara, and O'Connor); Palo Alto (Calif) Medical Research Foundation (Drs Araujo and Remington); and Stanford University School of Medicine, Palo Alto, Calif (Drs Araujo and Remington). Dr Rollins is a fellow of the E. A. Baker Foundation.

Arch Ophthalmol. 1983;101(3):455-457. doi:10.1001/archopht.1983.01040010455024

• Enzyme-linked immunosorbent assays were used to detect intraocular toxoplasmal antigen and antitoxoplasmal IgG antibodies in a rabbit model of experimental ocular toxoplasmosis. Toxoplasmal antigen could be detected in the vitreous humor of the infected eye at the height of clinical activity of the lesion. Antitoxoplasmal IgG antibodies were detected in the aqueous and vitreous humors of the infected eyes five weeks following the onset of toxoplasmic retinochoroiditis.

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