• Enbucrilate (butyl-2-cyanoacrylate; Histoacryl [West Germany], no comparable US product) is a tissue adhesive used in the management of corneal perforations that may have a therapeutic value in suppressing selective pathogens isolated, from corneal infections. In three patients with confirmed corneal infections, varying degrees of inhibition were observed. Bacteriostatic activity was most pronounced against gram-positive microorganisms, and no activity was observed against gram-negative organisms. It appears that this chemical adhesive provided an ancillary means of promoting healing of corneal perforations.
Eiferman RA, Snyder JW. Antibacterial Effect of Cyanoacrylate Glue. Arch Ophthalmol. 1983;101(6):958–960. doi:10.1001/archopht.1983.01040010958022
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.