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July 1983

Merkel Cell Tumor of the Eyelid: A Clinicopathologic Case Report

Author Affiliations

From the Departments of Ophthalmology (Drs Beyer and Dougherty) and Pathology (Drs Goodman and Dickersin), Harvard Medical School; the Massachusetts Eye and Ear Infirmary (Drs Beyer, Goodman, and Dougherty); and Massachusetts General Hospital (Dr Dickersin), Boston.

Arch Ophthalmol. 1983;101(7):1098-1101. doi:10.1001/archopht.1983.01040020100017

• We treated a patient who had clinical and pathological findings of a primary cutaneous tumor of the eyelid with histological and ultrastructural features of a Merkel cell carcinoma. This neoplasm is composed of cells that are thought to be derived from the neural crest and are found normally in the skin. While it may be a low-grade malignant neoplasm, this tumor can grow rapidly and metastasize. Histologically, it can mimic a metastatic undifferentiated small-cell carcinoma from the lung or other primary sites. To our knowledge, this is the first reported case involving an eyelid.

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