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November 1983

Intrastromal Noninflammatory Bacterial Colonization of a Corneal Graft

Author Affiliations

From the Departments of Ophthalmology, (Drs Gorovoy and Stern and Mr Allen) and Pathology (Dr Hood), University of Florida College of Medicine; and the Veterans Administration Medical Center (Dr Hood), Gainesville.

Arch Ophthalmol. 1983;101(11):1749-1752. doi:10.1001/archopht.1983.01040020751018

• Progressive branching, needlelike stromal opacities were observed within a corneal transplant. Analysis of the corneal button by light microscopy and transmission electron microscopy disclosed a localized epithelial ingrowth into the stroma at a suture tract accompanied by intrastromal pockets of gram-positive cocci extending across the cornea. No inflammatory reaction was found in the areas of bacterial colonization. To our knowledge, noninflammatory bacterial colonization of the stroma of a corneal transplant has not been previously described.

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