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January 1984

β-Irradiation of Choroidal Melanoma-Reply

Author Affiliations

Leipzig, East Germany

Arch Ophthalmol. 1984;102(1):19-20. doi:10.1001/archopht.1984.01040030009003

In Reply.  —My article was not meant to answer all questions regarding the melanoma problem. The fact that the survival rate of the patients treated with 106Ru/106Rh β-ray applicators was 85.1% after five years and 71.9% after ten years and thus significantly better than that of primarily enucleated patients with comparably sized tumors (68% after five years) should not remain without any consequence for the treatment of choroidal melanomas.It is true that statistically exact results of a comparison of two kinds of therapy would have to be based on two randomized groups of patients, which, however, will hardly be possible in the near future because of the rareness of the disease.This is the reason why, out of a group of 885 primarily enucleated patients, I selected 241 patients whose choroidal melanomas were of comparable size with those of the patients treated with 106Ru/

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