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January 1984

Betaxolol and Timolol: A Comparison of Efficacy and Side Effects

Author Affiliations

From the Duke University Eye Center, Durham, NC (Drs Berry and Shields); and the Department of Ophthalmology, Oregon Health Sciences University, Portland (Dr Van Buskirk).

Arch Ophthalmol. 1984;102(1):42-45. doi:10.1001/archopht.1984.01040030026028

• Betaxolol hydrochloride, 0.5%, and timolol maleate, 0.5%, were compared in a 26-week randomized, double-masked study involving 46 patients with primary open-angle glaucoma. The two drugs were comparable with regard to both intraocular pressure-lowering efficacy and side effects. Since betaxolol is a selective β1-adrenergic antagonist, it may be advantageous for patients in whom β2-blockade could be harmful.

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