• 2′-O-glycylacyclovir, a water-soluble ester derivative of acyclovir, has proved efficacious in the topical treatment of epithelial and stromal herpes simplex keratitis, and iritis therewith associated, when administered as a 1% eyedrop formulation to rabbits.
Maudgal PC, De Clercq K, Descamps J, Missotten L. Topical Treatment of Experimental Herpes Simplex Keratouveitis With 2′-O-glycylacyclovir: A Water-Soluble Ester of Acyclovir. Arch Ophthalmol. 1984;102(1):140–142. doi:10.1001/archopht.1984.01040030118049
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