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February 1984

Contact Lens Wear-Reply

Arch Ophthalmol. 1984;102(2):194-195. doi:10.1001/archopht.1984.01040030148011

In Reply.  —We appreciate the comments of Dr Shahinian. We do, however, have a few responses to make. First, the syndrome that we, and many others, have described is different from that described by Mondino and Groden' and Binder et al.2 Both of those reports describe an acute hypersensitivity reaction with an onset within the first two weeks of soft contact lens wear and with symptoms occurring on rechallenge with the contact lenses within hours. We agree that asymmetry may be marked in the patients with the soft contact lens-related SLK syndrome. The corneal epithelial pattern, in our experience, takes many months to clear and we have had one patient who has had persistent changes now for more than 18 months. Although we agree that thimerosal probably plays an important role in the syndrome, we have had a number of patients who, on rechallenge with new lenses and

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