[Skip to Navigation]
February 1984

Bacterial Endophthalmitis After Closed Vitrectomy

Author Affiliations

From the Eye Research Institute of Retina Foundation; Massachusetts Eye and Ear Infirmary, Harvard Medical School; and Retina Associates, Boston.

Arch Ophthalmol. 1984;102(2):207-210. doi:10.1001/archopht.1984.01040030157016

• Four cases of bacterial endophthalmitis occurred after more than 2,800 closed vitrectomies. Despite vigorous antibiotic therapy, all four eyes were lost. The poor outcome seems to result from difficulties in diagnosing this condition in its early stages. Important clinical indications, such as orbital pain, corneal edema and infiltrate, excessive intraocular inflammatory reaction, hypopyon, and diminished fundus reflex, are often masked by the usual postoperative course. According to our study, the incidence of endophthalmitis after closed vitreous surgery is 0.14%. Three of the four patients with endophthalmitis were diabetic. Our clinical findings are compared with those in the four other cases reported in the literature.

Add or change institution