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May 1984

Multiple Evanescent White Dot Syndrome: I. Clinical Findings

Author Affiliations

From the Departments of Ophthalmology, Northwestern University (Dr Jampol) and the University of Illinois Eye and Ear Infirmary (Drs Jampol, Sieving, Pugh, and Fishman) Chicago. Dr Sieving is currently with the Department of Ophthalmology, University of California, San Francisco.

Arch Ophthalmol. 1984;102(5):671-674. doi:10.1001/archopht.1984.01040030527008

• We examined 11 young patients with unilateral ocular findings that included multiple white dots at the level of the retinal pigment epithelium (RPE) or the deep retina, vitreal cells, RPE granularity in the macula, reduced visual acuity, electroretinogram (ERG) and early receptor potential (ERP) amplitudes, and fluorescein leakage from disc capillaries and late staining of the RPE. Recovery of visual function included a dramatic improvement in ERG and ERP amplitudes over several weeks. The etiology of this syndrome remains uncertain; there is no definite evidence of systemic involvement.

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