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June 1984

Aminocaproic Acid

Author Affiliations

New Orleans

Arch Ophthalmol. 1984;102(6):818-820. doi:10.1001/archopht.1984.01040030644002

To the Editor.  —We discussed with much interest the article entitled "Aminocaproic Acid Decreases Secondary Hemorrhage After Traumatic Hyphema" by McGetrick et al1 in our monthly journal club. The results of the study, although impressive, raised a number of questions that the article did not address.First, we were curious as to why 46 of the 49 patients in this 1½-year study had manifesting hyphemas filling less than 25% of the anterior chamber. Did most of the patients with hyphemas filling greater than 25% of the anterior chamber "require immediate surgical intervention"? In view of this select population, is it correct to extrapolate the effects of the aminocaproic acid to hyphemas greater than 25% as McGetrick et al did when they "strongly suggest that aminocaproic acid be used routinely in the management of nonperforated traumatic hyphemas"? Read2 cautioned that "systemic aminocaproic acid should be used only in hyphemas