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June 1984

Autosomal Dominant Exudative Vitreoretinopathy

Author Affiliations

Nijmegen, Holland

Arch Ophthalmol. 1984;102(6):824. doi:10.1001/archopht.1984.01040030650007

To the Editor.  —In their article in the October Archives, Feldman et al1 confirmed the extreme variability of clinical signs of autosomal dominant exudative vitreoretinopathy. Their findings agree with observations of other recent studies of (autosomal) dominant exudative vitreoretinopathy.2,3Feldman et al1 reported the occurrence of intraretinal white deposits. We observed similar lesions and agree that these lesions are almost confined to the avascular areas of the peripheral retina.4 Biomicroscopically, these lesions seem to be gliotic rather than exudative.In our study, intraretinal and subretinal exudates were found in only 16 of 141 eyes with dominant exudative vitreoretinopathy.4 The disease seems to be not so exudative as its denomination suggests.We concluded from our study that dominant exudative vitreoretinopathy is a developmental disorder of the retinal vascular system. The disease has not the characteristics of a slowly progressive vitreoretinal degeneration. The developmental disorder probably affects