• Photoradiation therapy (PRT) is a new technique that is currently under investigation for the treatment of a variety of solid malignant tumors. The technique involves systemic administration of hematoporphyrin derivative (HpD), a photosensitizing compound that is preferentially retained by malignant cells and photoactivation of the neoplasm with red light (630 nm) to achieve selective destruction of cancer cells. We used HpD PRT for seven patients with malignant melanoma of the uvea and conclude that initial results of HpD PRT for uveal malignant melanoma are encouraging and justify further investigation.
Tse DT, Dutton JJ, Weingeist TA, Hermsen VM, Kersten RC. Hematoporphyrin Photoradiation Therapy for Intraocular and Orbital Malignant Melanoma. Arch Ophthalmol. 1984;102(6):833–838. doi:10.1001/archopht.1984.01040030653011
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: