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July 1984

Herpes Zoster Ophthalmicus and Acquired Immune Deficiency Syndrome

Author Affiliations

From the Departments of Ophthalmology (Drs Cole and Meisler) and Rheumatic and Immunologic Disease (Dr Calabrese), Cleveland Clinic Foundation; the Jules Stein Eye Institute and the Department of Ophthalmology, UCLA School of Medicine (Drs Holland and Mondino); and the Department of Dermatology, University of California, San Francisco (Dr Conant).

Arch Ophthalmol. 1984;102(7):1027-1029. doi:10.1001/archopht.1984.01040030829026

• Acquired immune deficiency syndrome (AIDS) is a recently recognized disease characterized by abnormalities in cell-mediated immunity that predispose affected persons to severe opportunistic infections and unusual malignant neoplasms. We describe four cases of herpes zoster ophthalmicus in four previously healthy homosexual men. Two had signs and symptoms consistent with AIDS, and two had signs and symptoms of a lymphadenopathic syndrome associated with AIDS. We suggest that underlying AIDS be considered in young, healthy persons with herpes zoster ophthalmicus and no known cause of immunosuppression.