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August 1984

Retinopathy and Systemic Lupus Erythematosus

Arch Ophthalmol. 1984;102(8):1120-1121. doi:10.1001/archopht.1984.01040030902004

To the Editor.  —Systemic lupus erythematosus (SLE) is a collagen vascular disease characterized by immune complex deposition in multiple organ systems. In most cases, ocular involvement correlates with the patient's general medical condition.1-3 We describe, however, a patient with minimal SLE in whom bilateral rapidly progressive ocular disease developed, resulting in profound visual loss.

Report of a Case.  —A 31-year-old woman had a diagnosis of SLE made two years previously and was admitted to Lenox Hill Hospital, New York, in May 1983. One week prior to admission, despite a maintenance dose of 40 mg/day of oral prednisone, intermittent myalgias developed and the patient experienced loss of vision in both eyes. Physical examination disclosed discoid erythematous lesions of the skin. Visual acuity in each eye was hand motions, with weak pupillary reactions to light. The fundi revealed bilateral papillitis, diffuse, round, inflammatory infiltrates (deep in the retina or in the

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