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February 1985

The Histopathology of Familial Exudative Vitreoretinopathy: A Report of Two Cases

Author Affiliations

From the Palo Alto (Calif) Medical Foundation (Dr Boldrey); the Division of Ophthalmology, Stanford (Calif) University (Drs Boldrey and Egbert); the Bascom Palmer Eye Institute, Miami (Dr Gass); and the Department of Ophthalmology, Medical College of Georgia, Augusta (Dr Friberg). Dr Friberg is now with the University of Texas Health Science Center, Dallas.

Arch Ophthalmol. 1985;103(2):238-241. doi:10.1001/archopht.1985.01050020090029

• Two eyes were enucleated for angle-closure associated with familial exudative vitreoretinopathy. Characteristic features included total retinal detachment, peripheral retinal vascular proliferation, and a fibrovascular preretinal membrane. Angle-closure glaucoma developed in one case when sudden massive subretinal hemorrhage, associated with abnormal intraretinal vessels, produced anterior displacement of the lens-iris diaphragm; in the second case, angle-closure was associated with the development of rubeosis iridis. Intraretinal inflammatory cells and exudates were also seen in the enucleated eyes.

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