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April 1985

Compliance and Prognosis in Glaucoma

Arch Ophthalmol. 1985;103(4):504. doi:10.1001/archopht.1985.01050040046014

Poor compliance is an important limiting factor in the medical management of many chronic diseases. Yet, we have little information about defaulting from treatment regimens in ophthalmology. In part, this reflects methodologic problems of measuring compliance with topical ophthalmic medication. The recent development of eyedrop medication monitors allows us, for the first time, to make accurate and objective measurements of defaulting in ophthalmology.1-3 The initial studies have been restricted to pilocarpine and indicate a high rate of defaulting in terms of missed doses and inadequate time spacing of doses.4,5

See also p 529.

Good compliance is not an end in itself. The clinician must relate compliance to disease prognosis, especially if he or she is considering vigorous interventions to reduce defaulting. In an article published in this issue of the Archives, Granström6 finds little relationship between compliance with 4% pilocarpine treatment prescribed three times daily and progression