• One hundred patients with ocular occlusive vascular disease were studied by intravenous digital subtraction angiodraphy (IV DSA). In 17 patients with transient monocular blindness, 65% showed ipsilateral carotid atheroma. The degree of carotid stenosis was greater than 70% in eight of the 17 patients. Severe unilateral or bilateral stenosis was demonstrated in 70% of ten patients with chronic retinal artery obstruction, ie, venous stasis retinopathy or orbital hypoxia. An ipsilateral carotid artery source of emboli or substantial degree of stenosis was documented in 50% of 48 patients with acute retinal artery obstruction. Little or no carotid disease was found in 72% of 25 patients with retinal vein obstruction. The greatest value of IV DSA is in the management of patients with transient monocular blindness.