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June 1985

Conjunctival Nodules Associated With Onchocerciasis

Author Affiliations

From the Department of Ophthalmology, Pacific Medical Center, San Francisco. Dr Semba is now with the Wilmer Ophthalmological Institute, The Johns Hopkins Hospital, Baltimore.

Arch Ophthalmol. 1985;103(6):823-824. doi:10.1001/archopht.1985.01050060083031

• A 14-year-old native of Ethiopia with previously treated onchocerciasis moved to California where he was examined for evidence of persisting nematode infestation. Skin and conjunctival biopsy specimens initially disclosed no abnormalities. Subsequently, conjunctival nodules developed, and a biopsy specimen of one of these revealed microfilariae of Onchocerca volvulus lying adjacent to a necrotic eosinophilic granulomatous inflammatory nodule. To our knowledge, nodules of this type have not heretofore been reported to be a notable feature of ocular onchocerciasis. This type of inflammation has a relationship to degenerating microfilaria in onchocerciasis and in other nematode infestation.

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