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July 1985

Unsuccessful Laser Cyclophotocoagulation for Glaucoma in Aniridia

Arch Ophthalmol. 1985;103(7):890. doi:10.1001/archopht.1985.01050070016006

To the Editor.  —Aniridia is an uncommon bilateral ocular disorder affecting not only the iris but also the cornea, anterior chamber angle, lens, retina, and optic nerve. The reported incidence of glaucoma in aniridia is 6% to 75%.1-5 As a rule, congenital glaucoma is not found in infants with aniridia but may develop during childhood. Ophthalmologists believe that a progressive change in the anterior chamber angle during the first decades of life may lead to glaucoma.

Report of a Case.  —A 13-year-old boy with aniridia was referred to our glaucoma department. An examination of his right eye revealed severe glaucoma, which was resistant to any conservative therapy. The pressure of his left eye could be regulated with 0.25% timolol maleate twice daily. According to the difference in pressure in his right eye vs his left eye, the chamber angle of the more severely affected right eye was extensively crowded

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