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July 1985

Prevention of Intraocular Pressure Elevation Following Neodymium-YAG Laser Posterior Capsulotomy

Author Affiliations

From the Glaucoma Consultation Service, Massachusetts Eye and Ear Infirmary, and the Department of Ophthalmology, Harvard Medical School, Boston.

Arch Ophthalmol. 1985;103(7):912-915. doi:10.1001/archopht.1985.01050070038026

• Thirty-two eyes of 32 patients were treated with 0.5% timolol, 2% pilocarpine, or normal saline five and 30 minutes following neodymium-YAG laser posterior capsulotomy in a randomized, double-masked study. Mean maximum intraocular pressure (IOP) elevation was 8 2 mm Hg following treatment with normal saline, 5 3 mm Hg following treatment with 2% pilocarpine, and 1 ± 2 mm Hg following treatment with 0.5% timolol. Fewer patients treated with 0.5% timolol developed an IOP elevation of 5 mm Hg or more than control patients. One aphakic patient treated with 0.5% timolol developed a maximum IOP greater than or equal to 40 mm Hg. We found that treatment with 0.5% timolol after neodymium-YAG laser posterior capsulotomy provides partial protection from IOP elevation.

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