—Dr Wilensky has described a complication in a patient referred to the New York Hospital/ Cornell Medical Center for therapeutic ultrasound treatment. In our recent article describing the initial clinical results of the ultrasound treatment on our first 42 patients with a minimum three-month follow-up, all complications and side effects noted at the time of manuscript preparation are discussed.1 The clinical trial has continued, and to date over 160 patients have been treated. Our development of this new treatment modality has afforded us the unique opportunity to assess prognostic variables and risk factors in a purely prospective manner. Ongoing exploratory data analysis has identified three cases of visible scleral defects or staphylomas in adults. In the 16 patients aged 15 years or younger who were treated, visible scleral defects were noted in four (including Dr Wilensky's patient), and is related inversely to treatment efficacy. As the sample
Coleman DJ. Staphyloma Formation as a Complication of Ultrasound Treatment in Glaucoma-Reply. Arch Ophthalmol. 1985;103(8):1113. doi:10.1001/archopht.1985.01050080025010
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