• We present an overview concerning the current status of photodisruptive methods used in the treatment of pathologic changes in the vitreous space. In one series of 320 cases studied, 65% of the planned dissections of pathologic structures were successful. In a second series of 34 more complicated cases, the success rate was even lower. Complications included 15 retinochoroidal hemorrhages and one damaged posterior lens capsule. When one compares optical-surgical methods with conventional methods, it is obvious that the former aim at achieving goals that are less ambitious than those of classic vitrectomy and, in many cases, serve only to prepare for— and facilitate—a classic vitrectomy. By definition, laser vitreolysis dissects, but cannot remove, the fragments of disrupted structures from the eyeball. However, despite the obvious risks, photodisruptive laser surgery is considered less dangerous than is classic vitrectomy because photodisruption is a "noninvasive" procedure. Since laser vitreolysis is able to solve a number of clinical problems, obviating the need for vitrectomy, the former procedure should receive increasing attention for the treatment of pathologic problems in the vitreous cavity.
Fankhauser F, Kwasniewska S, van der Zypen E. Vitreolysis With the Q-Switched Laser. Arch Ophthalmol. 1985;103(8):1166–1171. doi:10.1001/archopht.1985.01050080078025
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