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September 1985

Intravenous Pyogenic Granuloma of the Ocular Adnexa: Report of Two Cases and Review of the Literature

Author Affiliations

From the Department of Pathology, the Methodist Hospital (Drs Truong and Font), the Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine (Dr Font), Houston; and the Registry of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC (Dr Font).

Arch Ophthalmol. 1985;103(9):1364-1367. doi:10.1001/archopht.1985.01050090116045

• Intravenous pyogenic granuloma is a recently described form of pyogenic granuloma (PG) in which the angiomatous proliferation is confined entirely within the lumen of a vein. To our knowledge, only four cases involving the ocular adnexa, including two that we encountered, have been described. Histologically, this benign lesion is similar to PG of other locations and is characterized by lobular congeries of capillaries embedded in a fibromyxoid matrix containing scattered chronic inflammatory cells. The whole lesion appears as a single polypoid mass projecting into the lumen of a dilated vein. The histogenesis of this lesion remains obscure. Complete local excision is the treatment of choice. Intravenous PG can be differentiated from other intravascular fibroangiomatous proliferations, including intravascular papillary endothelial hyperplasia, intravenous atypical vascular proliferation, intravascular fasciitis, and organized thrombus.

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