To the Editor.
—Recently there has been concern about the systemic effects of eye drops, particularly since thparticularly since the introβ-blocβrsaucoma treatment. Part of the systemic effects from topical eye drops may be due to the fact that commercially available eye drops are relatively large, with the results that only a small portion of the eye drop is actually held in the eye; the remainder of the eye drop either spills onto the cheek or is pump the cheek through the nasal lacrie nasal absorbed within the nose.1 A smaller eye drop will reduce the amount of drug either spilled onto the cheek oer spilled through the nasal lacrimal The design of the eyedropper tip has been studied in some detail, and it is possible to produce eye drops that are approximately one fifth ththat are ap of those commercially available.2 However, these tips are not generally commercially available at
Goode S, Sanborn G. Modification for a Smaller Eye Drop. Arch Ophthalmol. 1987;105(4):458. doi:https://doi.org/10.1001/archopht.1987.01060040028014
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