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May 1987

Esotropia and Anomalous Retinocalcarine Projections

Arch Ophthalmol. 1987;105(5):613. doi:10.1001/archopht.1987.01060050031016

To the Editor.  —In a recent article on handedness and esotropia,1 I postulated that some cases of esotropia might be the result of anomalous retinocalcarine projections, perhaps analogous to those that have been found in the Siamese cat and in human albinos. In preparing the report, I inadvertently overlooked two publications that contained important and pertinent information concerning the issue of anomalous "wiring" in nonalbino human esotropia. I would like to correct this omission.McCormack,2 using visual-evoked potentials, found no evidence of abnormal cortical projections in four patients with esotropia whom he studied. He concluded that these patients did not show the abnormal patterns that had been demonstrated by similar electrophysiologic investigations of human albinos. Fitzgerald and Billson3 investigated the visual-evoked potentials in normal subjects, in patients with congenital esotropia, in patients with unilateral dissociated vertical deviation, and in patients with alternating dissociated vertical deviation. Although both

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