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May 1987

Familial Association of Prepapillary Vascular Loops

Arch Ophthalmol. 1987;105(5):614. doi:10.1001/archopht.1987.01060050032020

To the Editor.  —In the December 1986 issue of the Archives, a letter from Grossniklaus and colleagues1 described a mother and daughter with prepapillary vascular loops. The statement was made that no familial association with these vessels had been described. I would like to refer Grossniklaus et al to the article Drs Lambert, Shacklett, and I published in 1983,2 in which we described a family of five members, two of whom had prevascular arterior loops and two of whom had other retinal vascular abnormalities. We suggested an autosomal-dominant inheritance pattern because of the presence of an arterial loop in the proband, a vascular anomaly in each of the children available for examination, and an arterial loop in the granddaughter. We welcome these authors' identification of an additional case of this unusual syndrome.