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December 1987

Use of Impression Cytology in Neonatal Chlamydial Conjunctivitis

Author Affiliations

San Antonio, Tex

Arch Ophthalmol. 1987;105(12):1626. doi:10.1001/archopht.1987.01060120024005

To the Editor.  —Impression cytology is a simple, relatively atraumatic technique to study ocular surface cells. Although first reported as a way to acquire an imprint of secreting goblet cells, it has been used for goblet-cell study in a variety of ocular disease states.1 Recently, Maskin and Bode2 used electron microscopy with impression cytology to demonstrate typical subcellular inclusions in mucopolysaccharidosis patients. We now report a new potential clinical use for impression cytology.

Report of a Case.  —A 10-day-old female neonate presented in the emergency room with a three-day history of a hyperemic left eye. The mother stated that she and her infant were in good health. She denied genital symptoms. Although she did not receive any prepartum medical care, she denied any difficulty during her pregnancy and had an uneventful delivery by a midwife. According to the mother, prophylactic eye drops were placed in her baby's eyes.

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