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December 1987

Carcinoma In Situ With Previous Trachoma

Arch Ophthalmol. 1987;105(12):1636. doi:10.1001/archopht.1987.01060120034013

To the Editor.  —An immunohistochemical analysis of conjunctival biopsy specimens from monkeys inoculated with Chlamydia trachomatis has shown a large number of Tsuppressor/cytotoxic and T-helper cells.1 In light of this modulation of cell-mediated immunity by C trachomatis, we recently had the opportunity to study a patient who had carcinoma in situ of the limbus together with a history and physical findings of healed trachoma.

Report of a Case.  —The patient was a 70-year-old woman who initially presented to us complaining of left periorbital "numbness." As a child she had trachoma that resulted in several surgical procedures for correction of entropion/trichiasis. Her medical history also included hypertension, asthma, and a seizure disorder. Systemic medications included digoxin, phenytoin, albuterol, aspirin, and verapamil.Visual acuity with hyperopic correction was 20/40-2 OD and 20/50 OS. The superior tarsal conjunctivae displayed Arlt's lines. Additionally, the left upper tarsus was foreshortened. The superotemporal

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