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February 1988

Allergic Response to a Porcine Collagen Corneal Shield

Author Affiliations

Brookline, Mass

Arch Ophthalmol. 1988;106(2):171. doi:10.1001/archopht.1988.01060130181012

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To the Editor.  —To my knowledge, this is the first report of an allergic response to a porcine collagen corneal shield (Bio-Cor, Bausch & Lomb).

Report of a Case.  —A 93-year-old woman underwent extracapsular cataract extraction and placement of a posterior chamber intraocular lens and inferior punctal occlusion by cautery without complication. Postoperatively, mild anterior basement membrane changes became activated and progressive, and the patient also developed a punctate epithelial keratopathy of the inferior half of the cornea. This was presumed to be due to the stress of surgery and ocular reaction to preservatives in the therapeutic eyedrops. Ocular lubricants without preservatives were extensively applied. The patient did not respond to this therapy and a porcine collagen corneal shield was applied. The eye was patched for 24 hours.The patient returned in 72 hours with a bright red hyperemic eye, total punctate epithelial keratopathy, and red, inflamed, exfoliated lids. Treatment

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