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February 1988

Macular Degeneration: Is There a Nutritional Component?

Arch Ophthalmol. 1988;106(2):183-184. doi:10.1001/archopht.1988.01060130193022

Although the disciform type of senile macular degeneration (SMD) was first recognized in the last century,1 it was considered an uncommon condition; as recently as 1939, only 130 cases were reported in the literature.2 The clinical evolution of SMD was not understood, and concepts were based on morphologic findings of advanced cases. Hemorrhage in the subretinal space was recognized as an important feature,3 but neovascularization was thought to be secondary to fibrovascular organization of the blood.4 Although the term senile macular degeneration has been used since Haab5 in 1885 first described the clinical entity of pigmentary and atrophic changes in the macula, the close relationship between macular drusen6 and disciform macular degeneration was generally overlooked.7

See also p 192.

With the development of fluorescein fundus angiography, the evolution and morphology of SMD can be demonstrated during the lifetime of the patient. Utilizing this

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