• We treated two cases of retinal phototoxic damage created by the coaxial illumination of the operating microscope during vitrectomy surgery. These lesions were probably created at the end of the vitrectomy procedure, after intraocular manipulation had ceased. This critical period, while the sclerotomy sites were being closed, was estimated to last no longer than ten to 15 minutes. We recommend that the cornea be shielded during sclerotomy closure at the conclusion of those vitrectomy procedures with a clear liquid media and clear crystalline lens or pseudophakos.