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April 1988

Multiple Myeloma Involving the Iris

Arch Ophthalmol. 1988;106(4):524-526. doi:10.1001/archopht.1988.01060130570039

• Intraocular invasion by neoplastic plasma cells is a rare ophthalmic manifestation of plasma cell dyscrasias. A 67-year-old man who had documented multiple myeloma presented with an infiltration of the iris that simulated a nongranulomatous uveitis. Cytologic examination of the aspirate obtained by anterior chamber paracentesis demonstrated that the infiltrate was composed of neoplastic plasma cells.