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April 1988

Multiple Myeloma Involving the Iris

Author Affiliations

From the Oncology Service (Drs Shakin, Augsburger, and Shields), Department of Pathology (Dr Eagle), Retina Service (Dr Fischer), and General Ophthalmology Service (Dr Koepsell), Wills Eye Hospital, and the Department of Pathology (Dr Ehya), Jefferson Medical College, Thomas Jefferson University, Philadelphia.

Arch Ophthalmol. 1988;106(4):524-526. doi:10.1001/archopht.1988.01060130570039

• Intraocular invasion by neoplastic plasma cells is a rare ophthalmic manifestation of plasma cell dyscrasias. A 67-year-old man who had documented multiple myeloma presented with an infiltration of the iris that simulated a nongranulomatous uveitis. Cytologic examination of the aspirate obtained by anterior chamber paracentesis demonstrated that the infiltrate was composed of neoplastic plasma cells.