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April 1988

Latent Disseminated Blastomycosis With Choroidal Involvement

Author Affiliations

From the Department of Ophthalmology, Medical College of Wisconsin, Milwaukee (Drs Lewis and Aaberg), and the Department of Ophthalmology, University of Wisconsin, Madison (Dr Stevens). Dr Fary is in private practice in Fort Atkinson, Wis. Dr Lewis is now with the Wilmer Ophthalmological Institute, Baltimore. Dr Aaberg is now with Emory University, Atlanta.

Arch Ophthalmol. 1988;106(4):527-530. doi:10.1001/archopht.1988.01060130573040

• A 36-year-old man developed blurred vision and a cough five months after traveling to an area from where a large out-break of acute blastomycosis had been reported. Examination revealed a left choroidal lesion in the macular region, skin lesions on the right calf, and a left lung apical infiltrate. Histopathologic examination of the skin lesion demonstrated a granulomatous inflammation and broad-based, budding yeast characteristic of Blastomyces dermatitidis. Amphotericin B therapy produced a rapid resolution of both choroidal and pulmonary lesions. During a six-month follow-up, there was no evidence of recurrence.